Definitely. He's the most egotistical man on the planet.

[Sue joins Teddy in the air, riding a platform of invisible energy, heavy looking gloves of force covering her hands. Time to put Little Mac's boxing lessons to use. When they collide with the Doombots, Sue opens with a vicious uppercut, the energy on her fist adding a lot to the punch and sending the machine hurtling through the air]

I think if Reed was a villain, Doom'd be a hero, just because they can't work together.